Journal of Musculoskeletal Trauma

Short-term Treatment Comparison of Teriparatide and Percutaneous Vertebroplasty in Patients with Acute Osteoporotic Vertebral Compression Fractures: Joonoh Seo, Ki Youn Kwon, Bumseok Lee, Hoon-Sang Sohn; J Korean Fract Soc 2024;37(1):15-21. Published online January 31, 2024; DOI: https://doi.org/10.12671/jkfs.2024.37.1.15

Abstract PDF: Purpose
This study compared the 3-month treatment effects of teriparatide and percutaneous vertebroplasty for acute osteoporotic vertebral compression fractures.
Materials and Methods
A retrospective study was conducted on 76 patients diagnosed with acute osteoporotic vertebral compression fractures from January 1, 2020 to December 31, 2022. The patients were divided into the teriparatide group and the percutaneous vertebroplasty+alendronate group. The visual analog scale (VAS), Oswestry disability index (ODI), and height of the vertebrae anterior wall were measured before treatment and at 1 and 3 months after treatment.
Results
Of the 76 patients, 42 were treated with teriparatide, and 34 were treated with percutaneous vertebroplasty. The symptoms improved in both groups, with a decrease in the VAS and ODI scores at 1 and 3 months after treatment, respectively. On the other hand, there was no significant difference in the VAS, ODI score, and anterior vertebral body height between the two groups before treatment and at 1 and 3 months after treatment.
Conclusion
In the treatment of acute osteoporotic vertebral compression fractures, conservative treatment using teriparatide showed similar short-term (3 months) treatment results to percutaneous vertebroplasty in terms of improvement in back pain and function and degree of reduction in anterior vertebral body height.

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Intraspinal Extradural Cyst Subsequent to a Vertebral Compression Fracture - A Case Report -: Byeong Yeol Choi, Jong Eon Choi; J Korean Fract Soc 2020;33(2):105-109. Published online April 30, 2020; DOI: https://doi.org/10.12671/jkfs.2020.33.2.105

Abstract PDF: Although a rare entity, intraspinal extradural cyst can cause severe deficit via neural compression. After reviewing available literature, the authors report a rare case of cord compression by intraspinal extradural cystic mass that developed after an osteoporotic vertebral compression fracture. An 80-year-old female patient had undergone vertebroplasty for osteoporotic vertebral compression fracture of T12, subsequent to a minor fall. However, the patient complained about sustained pain and progressive weakness of lower extremities even after the procedure. Follow-up magnetic resonance imaging revealed an intraspinal extradural cystic lesion compressing the spinal cord, and the patient had to undergo a surgical intervention via the posterior approach. Symptoms were relieved postoperatively, with no recurrence during the 1-year follow-up.

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Treatment Options of Osteoporotic Vertebral Compression Fractures: Yu Mi Kim, Tae Kyun Kim, Dae Moo Shim, Kyeong Hoon Lim; J Korean Fract Soc 2018;31(3):114-121. Published online July 31, 2018; DOI: https://doi.org/10.12671/jkfs.2018.31.3.114

This paper reviews previous studies on the treatment of osteoporotic vertebral compression fractures in elderly patients to determine what factors should be considered for successful treatment. In osteoporotic vertebral compression fractures, the primary treatment is conservative treatments. Other treatments include osteoporosis treatment, pain control, orthosis, and physical therapy. Recently, percutaneous catheterization or balloon plasty is performed for rapid pain recovery and early ambulation. Percutaneous catheterization or balloon posterior plasty is effective in reducing pain and improving the activity ability. Surgical treatment should be considered in cases of nonunion or osteonecrosis, dent, deformation, and spinal cord compression after conservative treatment has failed. In surgical treatment, posterior spinal fixation and vertebroplasty are more advantageous in terms of the amount of bleeding, operation time compared to the anterior approach, but the most appropriate method should be selected through the patient's condition and understanding of each surgical method.

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Effects of Herbal Medicines on Bone Mineral Density Score in Osteoporosis or Osteopenia: Study Protocol for a Systematic Review and Meta-Analysis
Su Min Hong, Eun Jung Lee
Journal of Korean Medicine Rehabilitation.2021; 31(2): 49. CrossRef
Spinal Stability Evaluation According to the Change in the Spinal Fixation Segment Based on Finite Element Analysis
Cheol-Jeong Kim, Seung Min Son, Jin-Young Heo, Chi-Seung Lee
Journal of the Computational Structural Engineering Institute of Korea.2020; 33(3): 145. CrossRef

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Progression of Compression and Related Factors in Conservative Management of Osteoporotic Vertebral Compression Fractures: Young Do Koh, Jeong Soo Park; J Korean Fract Soc 2015;28(2):132-138. Published online April 30, 2015; DOI: https://doi.org/10.12671/jkfs.2015.28.2.132

Abstract PDF

PURPOSE
The purpose of this study is to determine the ideal period of brace application for thoracolumbar (T10-L2) osteoporotic vertebral compression fracture (OVCF) based on the progression of the vertebral compression with passage of time and to evaluate the factors associated with progression of thoracolumbar OVCF, when treated conservatively.
MATERIALS AND METHODS
This retrospective study included a total of 46 patients who were diagnosed with thoracolumbar OVCF and could be followed-up for at least 6 months. In this study, the increase of compression rate and the mean slope of compression rate per weeks were compared between two periods (from diagnosed date to 8 weeks and from 8 weeks to 6 months), as the standard point. Age, bone mineral density (BMD), osteoporosis treatment after injury, diabetes mellitus (DM) as underlying disease were also compared between two groups (setting up 15% as standard point of increase of compression rate, <15% and > or =15%). Statistical analyses were performed using the paired t-test to assess the increase of compression rate and using the linear mixed model to assess the mean slope change. The relationships between the factors and progression of compression were analyzed using t-test, chi-square test, and logistic regression analysis.
RESULTS
The increase of compression rate was 13.03% and 1.97% in each period and the difference between those two periods was 11.06% (p=0.00). At 8 weeks of follow-up, the mean slope was reduced by 1.12 (p=0.00). No statistically significant difference in related factors was observed between two groups.
CONCLUSION
Considering the increase of compression rate with passage of time, brace should be applied strictly for an initial 8 weeks. And age, BMD, osteoporosis treatment after injury, and DM as underlying disease are not predictors of progression of compression in vertebral fractures.

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The Factors between the Progression of the Compression Rate and Magnetic Resonance Imaging Findings in Osteoporotic Vertebral Fracture Patients Treated with Teriparatide
Taebyeong Kang, Seung-Pyo Suh, Jeongwoon Han, Byungjun Kang, Changhyun Park
Journal of the Korean Orthopaedic Association.2023; 58(5): 392. CrossRef
Effect of Weekly Teriparatide Administration Followed by Percutaneous Balloon Kyphoplasty on Post-Menopausal Osteoporotic Compression Fracture Treatment
Sung-Ha Hong, Seung-Pyo Suh, Woo Jin Shin, Seung Gi Lee, Byung Jun Kang
Journal of the Korean Orthopaedic Association.2022; 57(1): 35. CrossRef
Treatment Effect with Weekly Teriparatide in the Vertebral Compression Fractures in Patients with Severe Osteoporosis
Seok-Ha Hwang, Young-Kyun Woo, Ho-Seung Jeon, Seung-Pyo Suh, Joo-Young Kim, Jae-Nam Kim
Journal of the Korean Orthopaedic Association.2019; 54(6): 528. CrossRef
The Influence of Initial Magnetic Resonance Imaging Findings on the Compression Rate of Thoracolumbar Osteoporotic Vertebral Compression Fracture
Seok-Ha Hwang, Seung-Pyo Suh, Young-Kyun Woo, Ho-Seung Jeon, Ho-Won Jeong
Journal of the Korean Orthopaedic Association.2018; 53(4): 341. CrossRef
A Retrospective Clinical Survey of Vertebral Compression Fractures
Ji Hye Oh, Yun Kyu Lee, Jae Soo Kim, Hyun Jong Lee, Sung Chul Lim
Journal of Acupuncture Research.2018; 35(4): 219. CrossRef

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Osteoporotic Spinal Compression Fracture and Degree of Vitamin D Deficiency: Hong Sik Kim, Youn Ho Choi, Ki Chul Park, Ye Soo Park; J Korean Fract Soc 2013;26(1):27-31. Published online January 31, 2013; DOI: https://doi.org/10.12671/jkfs.2013.26.1.27

Abstract PDF

PURPOSE
The aim of the present study was to evaluate the degree of serum vitamin D deficiency in patients with osteoporotic spinal compression fracture and correlation of serum vitamin D level with several variables.
MATERIALS AND METHODS
The medical records of 134 patients with osteoporotic spinal compression fracture, diagnosed at our hospital between October 2008 and June 2011, were reviewed. Serum 25(OH)vitamin D3 was used to evaluate the status of vitamin D level. Serum 25(OH)vitamin D3 level was compared and analyzed according to sex, the number of fractured vertebral body, living environment, and the season of injury. The correlation between vitamin D level and age, bone mineral density, and bone turnover marker were evaluated.
RESULTS
In the serum 25(OH)vitamin D3, 87 patients (65%) associated with osteoporotic spinal compression fracture had an insufficient level. Vitamin D level was the lowest in winter, the highest in summer, and significantly higher in the living home than nursing home. Vitamin D level was negatively correlated with age (r=-0.201, p=0.02) and positively correlated with bone mineral density (r=0.217, p=0.012).
CONCLUSION
Evaluation of vitamin D level in osteoporotic vertebral compression fracture patients may be helpful in planning the treatment of the patients. For insufficient vitamin D level, the adequate sun exposure and supplement of vitamin D may be used.

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Vitamin D Status according to the Diseases in Hospitalized Rehabilitation Patients: Single Center Study
Hanbit Ko, Jin Hee Nam, Soo-kyung Bok
Brain & Neurorehabilitation.2019;[Epub] CrossRef

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Cement Leakage into Disc after Kyphoplasty: Does It Increases the Risk of New Adjacent Vertebral Fractures?: Hoon Sang Sohn, Seong Kee Shin, Eun Seok Seo, Kang Seob Chang; J Korean Fract Soc 2011;24(4):361-366. Published online October 31, 2011; DOI: https://doi.org/10.12671/jkfs.2011.24.4.361

Abstract PDF: PURPOSE
This study aims to investigate the relationship between cement leakage into the disc during percutaneous balloon kyphoplasty and subsequent compression fractures in adjacent vertebrae during treatment of osteoporotic vertebral compression fracture.
MATERIALS AND METHODS
103 patients (118 vertebrae) who have been treated with balloon kyphoplasty due to osteoporotic compression fracture from June 2007 to July 2010 were retrospectively analyzed. The group was composed of 13 males and 90 females. The mean age was 75 years (57~95 years). The mean follow-up period was 10 months (6~30 months). Patients were divided into two groups; one with cement leakage into the disc and the other without cement leakage into the disc. The study was performed to determine whether subsequent compression fractures in adjacent vertebrae were related to several factors.
RESULTS
The cement leakages into the disc occurred in 16 of 118 vertebrae. Of the 16 vertebrae with cement leakage into the disc, 5 (31%) had subsequent adjacent vertebral compression fractures; however, of the 102 vertebrae in which cement leakage did not occur, only 11 (11%) had subsequent adjacent vertebral compression fractures (p<0.05). Of the 16 vertebrae with cement leakage into the disc, subsequent adjacent vertebral compression fractures occurred 1 vertebrae of 10 vertebrae with definite trauma history. Out of the 6 vertebrae with cement leakage and no definite trauma history, 4 vertebrae (67%) had subsequent adjacent vertebral compression fractures (p<0.05).
CONCLUSION
The cement leakage into the disc significantly increases the incidence of subsequent adjacent vertebral compression fractures. Most of the subsequent fractures occurred in the early post-operative period. When cement leakage into the disc occurred in patients with no definite trauma history such as slip down, the incidence of subsequent adjacent vertebral compression fracture increased significantly.

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False Negative Bone Scan in 56-year Old Man with L2 Compression Fracture Performed 78 Hours after Trauma: A Case Report: Jeong Gook Seo, Hae Kyun Joo, Sung Tae Kim; J Korean Fract Soc 2010;23(4):386-390. Published online October 31, 2010; DOI: https://doi.org/10.12671/jkfs.2010.23.4.386

Abstract PDF: It is very rare that the bone scan after 72 hours from the trauma doesn't exhibit the increased radio-nuclide uptake in the patient with fracture. The purpose of this study is to report the case that indicate the false negative finding in the bone scan performed after 78 hours from the trauma in the 56-year-old man with L2 compression fracture, including a review of the relevant literatures.

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The Effect of Adjacent Vertebral Body on Vertebroplasty for Compression Fracture: Yong Chan Kim, Ho Geun Chang, Kee Byung Lee; J Korean Fract Soc 2010;23(1):97-103. Published online January 31, 2010; DOI: https://doi.org/10.12671/jkfs.2010.23.1.97

Abstract PDF

PURPOSE
To analyze the effect of adjacent vertebral body on local sagittal segment in performing vertebroplasty for thoracolumabr vertebral compression fracture on the terms of radiological results.
MATERIALS AND METHODS
We experienced 61 cases of T12 and L1 Compression fracture between June 2003 and November 2005. We classified with 3 groups; no collapse of adjacent body, collapse of adjacent upper body, and collapse of adjacent lower body. The measuring factors were anterior, middle, posterior vertebral height, wedge angle and local kyphotic angle.
RESULTS
In group I, Increase rate of anterior, middle, posterior vertebral height and restoration rate of wedge angle, and local kyphotic angle were average of 0.41%, 0.31%, 0.16%, 1.47%, ?3.48% respectively. Group II was -3.19%, 0.11%, -3.02%, -1.23%, -4.63%. Group III was -2.28%, 4.72%, -1.01%, -2.41%, -13.12%. There are no significant differences among the groups except local kyphotic angle in Group III statistically.
CONCLUSION
The previous wedged collapse of adjacent vertebral body do not affect local sagittal segment performed vertebroplasty in the thoracolumbar compression fracture. However the previous wedged collapse of adjacent lower body affect significantly local kyphotic angle.

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Survival Rate and Risk Factor Analysis in Patients Who Experience a New Fracture after Kyphoplasty
Jung-Hoon Kim, Dong-Hyok Kim
Journal of Korean Society of Spine Surgery.2018; 25(3): 99. CrossRef

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The Factors that Affect the Deformity Correction of Vertebral Body during Kyphoplasty of Osteoporotic Vertebral Compression Fracture: Young Do Koh, Jong Seok Yoon, Sung Il Kim; J Korean Fract Soc 2008;21(1):57-61. Published online January 31, 2008; DOI: https://doi.org/10.12671/jkfs.2008.21.1.57

Abstract PDF: PURPOSE
To study which factors affect the deformity correction of vertebral body during kyphoplasty procedure.
MATERIALS AND METHODS
25 osteoporotic vertebral compression fractures were treated with balloon kyphoplasty from October 2006 to May 2007. Lateral radiographs were taken at 5 different stages with preoperative lateral decubitus position, after placing the patient in prone position on an operation table, after inflating balloon, after deflation and removal of the balloon, after inserting the cement. Then we analyzed the compression ratios and kyphotic angles of the vertebral bodies in each stage.
RESULTS
Placing the patient in prone position showed significant postural reduction in kyphotic angle and restorement of the anterior and middle body height. The inflation of the balloon demonstrated significant reduction of kyphotic angle and restorement of the anterior and middle body height. After the deflation, anterior and middle body height has decreased significantly. After the deflation, the kyphotic angle and the anterior and middle body heights were not restored signigicantly compared with those of initial prone position.
CONCLUSION
Vertebral height and kyphotic angle were partially recovered by inflating the balloon, but the correction was lost after deflating the balloon. Statistically, the body deformity was not restored significantly after deflating the balloon compared with that of intraoperative prone position. Therefore, we concluded that, in kyphoplasty of osteoporotic compression fractures, the postural reduction is the most important factor in deformity correction of fractured vertebral bodies.

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Factors Confluencing the Result of Percutaneous Balloon Kyphoplasty in Osteoporotic Thoracolumbar Compression Fracture: Jung Hee Lee, Dae Woo Hwang, Jae Heung Shin, Woo Sung Hong, Ju Wan Kim; J Korean Fract Soc 2007;20(1):76-82. Published online January 31, 2007; DOI: https://doi.org/10.12671/jkfs.2007.20.1.76

Abstract PDF

PURPOSE
We are to find the method to objectify postoperative prognosis, analyzing the factors confluencing the result of kyphoplasty in osteoporotic vertebral compression fracture (OVCF).
MATERIALS AND METHODS
Our study included 50 patients (55 vertebral bodies) who have undergone kyphoplasty from Sep. 2004 until Oct. 2005. We divided in the group according to bone mineral density (BMD), compression rate, recovery rate and cement leakage. We verified the significance of each group, using independent t-test, and ANOVA test among observers.
RESULTS
We performed kyphoplasty on 55 vertebral bodies, 12 cases with more than 0.4 g/cm2 in BMD (mean: 0.53 g/cm2) and their mean preoperative compression rate (CR), immediate postoperative recovery rate (RR-IPO), and recovery rate after 6 months (RR-6M) was each 30.58%, 12.35%P, 9.93%P. 15 cases under 0.4 g/cm2 (mean 0.31 g/cm2), and their CR, RR-IPO and RR-6M was 26.73%, 11.77%P, 5.26%P respectively. The p-value was 0.004. Another studies according to CR, RR-IPO and leakage of cement revealed the better results in the cases of the lower CR, the smaller reduction and abscecnce of cement leakage, but statistically insignificant (p=0.309, 0.069, 0.356).
CONCLUSION
Preoperative BMD was most important factor that confluencing postoperative radiological result in OVCF. Other factors were also thought to be confluencing factors, but statistically insignificant..

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Cement Leakage into Disc after Kyphoplasty: Does It Increases the Risk of New Adjacent Vertebral Fractures?
Hoon-Sang Sohn, Seong-Kee Shin, Eun-Seok Seo, Kang-Seob Chang
Journal of the Korean Fracture Society.2011; 24(4): 361. CrossRef

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Comparison of the Result of Vertebroplasty and Conservative Treatment in Osteoporotic Vertebral Compression Fracture: Ye Soo Park, Woo Jin Cho, Jae Lim Cho; J Korean Fract Soc 2006;19(3):363-368. Published online July 31, 2006; DOI: https://doi.org/10.12671/jkfs.2006.19.3.363

Abstract

PURPOSE
To evaluate the results of vertebroplasty and conservative treatment in osteoporotic vertebral compression fractures.
MATERIALS AND METHODS
Patients were divided randomly into 2 groups; Group I (conservative treatment) and Group II (vertebroplasty). There are 14 cases in group I and 16 cases in group II. Radiologically, the progression of compression was observed. Clinical evaluation was done using Denis pain scale. In both groups, prolonged pain with nonunion or avascular necrosis that resulted in surgical intervention was evaluated as complication. In group II, the complication associated the procedures were evaluated.
RESULTS
Group II was superior to conservative treatment in terms of maintaining vertebral height radiologically. The characteristics of symptom improvement were the same in two groups. There were cement leakage among group II but they did not influence to the results. In group I, 2 subjects needed surgery due to prolonged pain. In group II, 1 subject needed surgery due to prolonged pain and there were 3 cement leakage cases which were insignificant.
CONCLUSION
In vertebroplasty group, complications associated the procedures were noted. In conservative treatment group, more patients needed operation. Therefore, we should be very prudent when we choose the treatment of the osteoporotic vertebral compression fracture.

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A Case Report of the Korean Medical Treatment of Dysphagia and Anorexia after Lumbar Compression Fracture
Hye-mi Jo, Eun-chang Lee, Hye-soo Youn, Choong-hyun Park, Da-young Han, Da-hae Jung, Jung-eun Lee
The Journal of Internal Korean Medicine.2022; 43(2): 219. CrossRef
A Retrospective Clinical Survey of Vertebral Compression Fractures
Ji Hye Oh, Yun Kyu Lee, Jae Soo Kim, Hyun Jong Lee, Sung Chul Lim
Journal of Acupuncture Research.2018; 35(4): 219. CrossRef
Lumbar Spine Fracture
Seung-Wook Back, Hyun-Joong Cho, Ye-Soo Park
Journal of the Korean Fracture Society.2011; 24(3): 277. CrossRef

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A Clinical Analysis of 260 Percutaneous Vertebroplasty in the Treatment of Osteoporotic Compression Fracture: Sang Hyuk Min, Myung Ho Kim, Hee Gon Park, Ho Dong Paik; J Korean Fract Soc 2006;19(3):357-362. Published online July 31, 2006; DOI: https://doi.org/10.12671/jkfs.2006.19.3.357

Abstract

PURPOSE
To evaluate retrospectively the results regarding pain relief, complication after percutaneous vertebroplasty, for an osteoporotic compression fractures.
MATERIALS AND METHODS
260 patients (male 55, female 260, mean age 69.4 years old) treated by percutaneous vertebroplasty in Dankook University Hospital from July 1997 to July 2004 were reviewed. We performed percutaneous vertebroplasty and observed the degree of pain relief using pain scale pre-/postoperation. we evaluate the complication by plain radiographs and computed tomography, ABGA and chest X-ray. we evaluate pain relief and complication for 1 week by follow-up plain radiographs. we recommended BMD follow-up per 1 year and osteoporosis medication at least 2 years. A clinical result was evaluated as excellent, good, fair, poor and visual analogue scale (VAS 0~10) for 1 year. We prefaced a statistical analysis by T-test using SPSS (version 11.0) correlating 1 week and 1 years effects.
RESULTS
73 (28.3%) of the patients were evaluated as excellent: 123 (45.5%), as good: 45 (17.8%), as fair; and 23 (8.5%), as poor, show 73.8% over good in 1 week. 76 (29.3%) of the patients were evaluated as excellent; 120 (44.3%), as good; 43 (16.8%), as fair; and 25 (9.6%), as poor in 1 year, show 73.6% over good result. 1 week follow-up and 1 year follow-up show similar results. 1 patient had death (hemothorax), 4 patients had arrhythmia, 15 patients (21 vertebrae) had fracture around vertebroplasty.
CONCLUSION
Percutaneous vertebroplasty using PMMA is valuable method in the treatment of osteoporotic compression fracture, providing immediately pain relief, long term pain relief, prevention of complication originated from long term traction and bed rest, unwearing brace and early ambulation.

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Comparison of Outcomes of Conservative Treatment, Early Vertebroplasty, and Delayed Vertebroplasty in Patients with Osteoporotic Vertebral Compression Fractures
Se-Hyuk Im, Young-Joon Ahn, Bo-Kyu Yang, Seung-Rim Yi, Ye-Hyun Lee, Ji-Eun Kwon, Jong-Min Kim
Journal of Korean Society of Spine Surgery.2016; 23(3): 139. CrossRef
Large Pulmonary Embolus after Percutaneous Vertebroplasty - A Case Report -
Sang Ho Moon, Soo Won Lee, Byoung Ho Suh, Sung Hwan Kim
Journal of Korean Society of Spine Surgery.2009; 16(1): 46. CrossRef
Risk Factors of New Compression Fractures in Adjacent Vertebrae after Percutaneous Vertebroplasty
Myung-Ho Kim, Sang-Hyuk Min, Suk-Ha Jeon
Journal of the Korean Fracture Society.2007; 20(3): 260. CrossRef

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Percutaneous Vertebroplasty in the Treatment of Osteoporotic Compression Fracture (99 Patients, 171 Vertebral Bodies): Chung Hwan Kim, Hyung Sun Ahn, Jae Kwang Hwang, Jung Suk Song, Eui Jung Bae; J Korean Fract Soc 2006;19(2):259-264. Published online April 30, 2006; DOI: https://doi.org/10.12671/jkfs.2006.19.2.259

Abstract: PURPOSE
This study was designed to compare the clinical and radiologic outcome of the patients who underwent percutaneous vertebroplasty among the groups based on follow-up period and BMD.
MATERIALS AND METHODS
A total of 99 patients (171 vertebral bodies) underwent percutaneous vertebroplasty from January 2001 to September 2003. The patients were divided into 3 groups by follow-up periods, and also divided into 2 groups by BMD. We investigated the difference of radiologic and clinical effects among the groups. Radiologic findings was assessed as vertebral height restoration rate and rate of reduction loss by measurement of the height of vertebral body. The clinical outcomes were graded into 5. The statistical analysis was done using Chi-squire test and Independent-samples T test.
RESULTS
Among the groups divided by follow-up period, there was no statistically significant difference of clinical and radiologic results except the rate of reduction loss between group I and group III (p>0.05). Between the groups divided by BMD, there was no statistically significant difference of clinical and radiologic results.
CONCLUSION
Percutaneous vertebroplasty with bone cement for the osteoporotic compression fracture is an efficient procedure and considered as technique producing pleasurable clinical and radiologic results regardless of follow up-period and BMD.

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Correlation between Progression of Compression and Bone Densiometry Index in Osteoporotic Compression Fracture of Thoracolumbar Spine: Jung Hoon Kim, Jeong Gook Seo, Jong Ho Ahn; J Korean Fract Soc 2006;19(2):254-258. Published online April 30, 2006; DOI: https://doi.org/10.12671/jkfs.2006.19.2.254

Abstract

PURPOSE
To evaluate whether progression of compression correlates with bone densiometry index in patients who were treated conservatively for osteoporotic compression fracture of thoracolumbar spine.
MATERIALS AND METHODS
Using the results of bone densiometry, 30 patients who were treated conservatively for osteoporotic compression fracture of thoracolumbar spine between March 2002 to March 2005 were categorized into 4 groups; above 80%, 70 to 80%, 60 to 70%, and below 60%. We compared the measurements of sagittal index and anterior vertebral height from the plain radiographs taken at the time of injury and following three consecutive months after the injury.
RESULTS
Patients with lower bone densiometry index had greater amount of compression at the time of injury and more rapid progression of compression. We also found that progression of compression was lowest during the first month after injury in all groups.
CONCLUSION
Patients with low bone densiometry index in osteoporotic thoracolumbar compression fracture are susceptible to more rapid progression of compression and should have early brace application and longer duration of treatment for osteoporosis.

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Comparison of Outcomes of Conservative Treatment, Early Vertebroplasty, and Delayed Vertebroplasty in Patients with Osteoporotic Vertebral Compression Fractures
Se-Hyuk Im, Young-Joon Ahn, Bo-Kyu Yang, Seung-Rim Yi, Ye-Hyun Lee, Ji-Eun Kwon, Jong-Min Kim
Journal of Korean Society of Spine Surgery.2016; 23(3): 139. CrossRef
Progression of Compression and Related Factors in Conservative Management of Osteoporotic Vertebral Compression Fractures
Young Do Koh, Jeong Soo Park
Journal of the Korean Fracture Society.2015; 28(2): 132. CrossRef

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Vertebroplasty in the Treatment of Osteoporotic Compression Fracture: More Than 1 Year Follow Up: Jaekwang Hwang, Chunghwan Kim, Joohyun Kim; J Korean Fract Soc 2004;17(4):368-373. Published online October 31, 2004; DOI: https://doi.org/10.12671/jkfs.2004.17.4.368

Abstract PDF

PURPOSE
To assess the clinical and functional outcome of the patients who underwent percutaneous vertebroplasty with bone cement for the osteoporotic compression fracture and who had been followed up for minimum 1 year.
MATERIALS AND METHODS
Among 110 patients who had been undergone percutaneous vertebroplasty with bone cement for osteoporotic compression fracture in Gangneung Asan Hospital from January 2001 to August 2002, 75 patients who had been followed up for more than 1 year were selected. And retrospectively, we analyzed the clinical and radiographic finding of 1 year, 2 year and 3 year follow-up. The patients were divided into 3 groups, the first group who have follow-up period of the from 1 to 2 years had 75 patients, the second group who the from 2 to 3 years, 49 patients, and the third group who the more than 3 years, 20 patients. We graded the clinical results to excellent, good, normal, fair and poor. Also, we assessed the height of vertebral body, the adjacent vertebral body fracture and the leakage of bone cement.
RESULTS
74 patients (98.6%) had the excellent or good results postoperatively. 69 patients (92%) of the first group, 46 patients (93.8%) of the second group and 16 patients (80%) of the third group had excellent or good results at last follow-up. There was no statistical correlation of each groups (p>0.05). In first group, the average height of body was 71.1% preoperatively, 73.5% postoperatively and 73.5% at follow-up. In second group, 71.5%, 75.5%, and 73.1%. In third group, 71.2%, 78.0% and 77.8%. There was no significant statistical correlation of each groups (p>0.05). 47cases (38.8%) had some leakage of cement immediate postoperatively. In 4 cases (7 vertebra), there were adjacent vertebral body fractures.
CONCLUSION
Based on the results of our study, percutaneous vertebroplasty is a useful method in the treatment for the osteoporotic compression fracture of vertebra body.

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Comparison of Outcomes of Conservative Treatment, Early Vertebroplasty, and Delayed Vertebroplasty in Patients with Osteoporotic Vertebral Compression Fractures
Se-Hyuk Im, Young-Joon Ahn, Bo-Kyu Yang, Seung-Rim Yi, Ye-Hyun Lee, Ji-Eun Kwon, Jong-Min Kim
Journal of Korean Society of Spine Surgery.2016; 23(3): 139. CrossRef
The Diagnosis of Osteoporotic Occult Vertebral Fracture and Vertebroplasty
Seong Jun Ahn, Bu Hwan Kim, Moo Ho Song, Seong Ho Yoo, Yeong Joon Kim
Journal of the Korean Fracture Society.2012; 25(3): 208. CrossRef
Risk Factors of New Compression Fractures in Adjacent Vertebrae after Percutaneous Vertebroplasty
Myung-Ho Kim, Sang-Hyuk Min, Suk-Ha Jeon
Journal of the Korean Fracture Society.2007; 20(3): 260. CrossRef
Compatibility of Self-setting DBM-CP Composites in Percutaneous Kyphoplasty
Jung Hee Lee
Journal of the Korean Fracture Society.2007; 20(3): 266. CrossRef

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Vertebroplasty for the Treatment of Painful Osteoporotic Compression Fractures: Young Woo Kim, Ho Guen Chang, Kee Byoung Lee, Yong nam Ji, Yong Beom Lee, Jeong Mo Ku; J Korean Fract Soc 2004;17(1):49-54. Published online January 31, 2004; DOI: https://doi.org/10.12671/jkfs.2004.17.1.49

Abstract PDF

PURPOSE
To evaluate results regarding pain relief, spinal stabilization, and complication after treatment with percutaneous vertebroplasty.
MATERIALS AND METHODS
108 patients (12 men, 96 women; aged 42~84 years) underwent 156 percutaneous injections of surgical cement into a vertebra (vertebroplasty) with fluoroscopic guidance in 119 procedures. All patients had severe pain,osteoporotic fractures and had failed medical therapy. Immediate and long-term pain response, spinal stability, and complications were evaluated. Assessment criteria were the changes over time (Days 3, 30, 90, 180) in visual analogue scale (VAS: 0~100 mm) and McGill-Melzack scoring system. The height of vertebral body was checked at three portions (anterior, middle, posterior) with lateral view of plain radiographs.
RESULTS
A statistically significant decrease of both VAS and McGill-Melzack scoring system was observed at Day 3. The results were also significant at Days 30, 90, and 180 both scales. We observed no adverse event, but 26 vertebral fractures had occured in the adjacent level during 12 months of follow-up. The leakage of cement was observed in 57 vertebral bodies (36.5%). But there was no neurological symptoms associated with cement leakage. The vertebral body height was increased after vertebroplasty.
CONCLUSION
Vertebroplasty is safe and effective, and have a useful role in the treatment of painful osteoporotic vertebral compression fractures that do not respond to conventional treatments. Continuous management of osteoporosis and patient education is mandantory to prevent subsequent fracture of the adjacent vertebral bodies.

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Comparison of Outcomes of Conservative Treatment, Early Vertebroplasty, and Delayed Vertebroplasty in Patients with Osteoporotic Vertebral Compression Fractures
Se-Hyuk Im, Young-Joon Ahn, Bo-Kyu Yang, Seung-Rim Yi, Ye-Hyun Lee, Ji-Eun Kwon, Jong-Min Kim
Journal of Korean Society of Spine Surgery.2016; 23(3): 139. CrossRef
The Factors that Affect the Deformity Correction of Vertebral Body during Kyphoplasty of Osteoporotic Vertebral Compression Fracture
Young-Do Koh, Jong-Seok Yoon, Sung-Il Kim
Journal of the Korean Fracture Society.2008; 21(1): 57. CrossRef
Compatibility of Self-setting DBM-CP Composites in Percutaneous Kyphoplasty
Jung Hee Lee
Journal of the Korean Fracture Society.2007; 20(3): 266. CrossRef

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Complications after Vertebroplasty of Treatment for Compression Fracture with Osteoporosis: Hee Gon Park, Myung Ho Kim, Moon Jib Yoo, Sung Chul Lee, Jin Young Park, Woo Yeon Hwang, Jin Woo An; J Korean Soc Fract 2003;16(4):534-540. Published online October 31, 2003; DOI: https://doi.org/10.12671/jksf.2003.16.4.534

Abstract PDF

PURPOSE
To evaluate the complications of percutaneous vertebroplasty using PMMA (polymethylmethacrylate) in the treatment of osteoporotic compression fractures.
MATERIALS AND METHODS
Authors reviewed 113 patients treated by percutaneous vertebroplasty from 1998 to 2001. After treatment, Simple x-ray and computed tomography were done of methods for analysis of complication, especially bone cement leakage.
RESULTS
In each case, we injected bone cement (PMMA) in one vertebra, average amount is 5.6 cc. The complications were 39 cases (34.5%): 1 case was dead by hemothorax, 1 case was arrhythmia, 12 cases were intercostals neuralgia, 7 cases were back pain, 2 cases were mild dyspnea, 14 cases were abdominal pain and 2 case were injection site pain. In follow-up x-ray and CT, bone cement (PMMA) leakage were 45 cases (39.8%).
CONCLUSION
Bone cement (PMMA) leakage can be cause of complications in vertebroplasty. We try to avoid the complication of bone cement leakage.

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A Review of Korean Medicine Treatment for Managing the Thoracolumbar Compression Fractures: A Retrospective Observational Study
Min-Jin Cho, Jiyun Lee, Myeong-Jong Lee, Hojun Kim, Kyungsun Han
Journal of Korean Medicine Rehabilitation.2023; 33(4): 109. CrossRef
Clinical and radiological outcomes of denosumab and teriparatide treatment in elderly patients with osteoporotic spinal compression fracture without vertebroplasty
Joo Young Jung, Byoung Hun Lee, Jong Young Lee, Hong Jun Jeon, Byung Moon Cho, Su Yeon Kim, Se Hyuck Park
Journal of Korean Society of Geriatric Neurosurgery.2021; 17(2): 69. CrossRef
A Retrospective Clinical Survey of Vertebral Compression Fractures
Ji Hye Oh, Yun Kyu Lee, Jae Soo Kim, Hyun Jong Lee, Sung Chul Lim
Journal of Acupuncture Research.2018; 35(4): 219. CrossRef
Survival Analysis of Conservative Treatement in Osteoporotic Vertebral Fracture
Young Do Koh, Jong-Oh Kim, Rag Gyu Kim, Dae Youn Kim, Nam-Ki Kim, Dong Jun Kim
Journal of Korean Society of Spine Surgery.2012; 19(4): 138. CrossRef
Factor Analysis Affecting the Leakage of Bone Cement After Vertebroplasty
Jae-Hoon Kim, Kyung-Jin Song, Tai-Seung Kim, Jae-Lim Cho, Ye-Soo Park
Journal of Korean Society of Spine Surgery.2010; 17(1): 13. CrossRef

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Vertebroplasty on osteoporotic compression fracture: Chunghwan Kim, Youngjoon Choi, Seungki Baek, Hyungsun Ahn, Jaekwang Hwang, Sujung Choi, Jaiwoo Cho, Kyeungjune Park, Hyeuntae Ahn; J Korean Soc Fract 2002;15(2):123-128. Published online April 30, 2002; DOI: https://doi.org/10.12671/jksf.2002.15.2.123

Abstract PDF

PURPOSE
Percutaneous vertebroplasty is the procedure of bone cement injection and allogenous bone graft for pain relief in case of compression fracture, hemangioma etc. Recently, osteoporotic compression fracture increases as the old age increase. We analyzed the postoperative clinical symptoms and radiologic findings.
MATERIALS AND METHODS
From Jan. 2000 to Apr. 2001, we have analyzed 111 osteoporotic compression fractures(59 patients) at Kangneung hospital. Before the procedure, we checked BMD, bone scan and CT. Most common fracture site was the thoracolumbar junction area. Fluoroscopic control was necessary for the cement injection to prevent cement leakage. The amount of cement injection was 4.7ml. We have studied the increase of vertebral body height, symptom recovery time & pain relief, postoperative complications.
RESULT
The vertebral body height was increased from 55.5% to 70.3% postoperatively and the symptom was improved in 48 persons at POD 1, 3 persons at postoperative 2 weeks, and 4 persons at postoperative 2 months. Most common complication was cement leakage to the epidural vessel, disc space, and spinal canal. But serious complication-spinal canal leakage- was only 1 case and had been improved after decompression.
CONCLUSION
Percutaneous vertebroplasty with bone cement(PMMA) is effective treatment in osteoporotic compression fracture, especially in pain relief.

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Outcome Comparison between Percutaneous Vertebroplasty and Conservative Treatment in Acute Painful Osteoporotic Vertebral Compression Fracture
Hwa-Yeop Na, Young-Sang Lee, Tae-Hoon Park, Tae-Hwan Kim, Kang-Won Seo
Journal of Korean Society of Spine Surgery.2014; 21(2): 70. CrossRef
Adjacent Vertebral Compression Fracture after Percutaneous Vertebroplasty
Chung-Hwan Kim, Jae-Kwang Hwang, Jun-Seok Park
Journal of Korean Society of Spine Surgery.2013; 20(4): 163. CrossRef
The Diagnosis of Osteoporotic Occult Vertebral Fracture and Vertebroplasty
Seong Jun Ahn, Bu Hwan Kim, Moo Ho Song, Seong Ho Yoo, Yeong Joon Kim
Journal of the Korean Fracture Society.2012; 25(3): 208. CrossRef
Factor Analysis Affecting the Leakage of Bone Cement After Vertebroplasty
Jae-Hoon Kim, Kyung-Jin Song, Tai-Seung Kim, Jae-Lim Cho, Ye-Soo Park
Journal of Korean Society of Spine Surgery.2010; 17(1): 13. CrossRef
Treatment of Combined Degenerative Lumbar Disease and Adjacent Vertebral Fracture
Jae-Lim Cho, IL-Hoon Sung, Seung-Wook Baek, Ye-Soo Park
Journal of Korean Society of Spine Surgery.2008; 15(4): 236. CrossRef

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The effect of percutaneous vertebroplasty with bone cement in the treatment of osteoporotic thoracolumbar compression fracture: Jae Do Kang, Kwang Yul Kim, Sang In Park; J Korean Soc Fract 2001;14(2):265-271. Published online April 30, 2001; DOI: https://doi.org/10.12671/jksf.2001.14.2.265

Abstract PDF

PURPOSE
To analyzed the degree of pain relief of 40 patients with osteoporotic thoracolumbar compression fracture treated by percutaneous vertebroplasty with bone cement.
MATERIALS AND METHODS
We studied 40 cases of the osteoporotic thoracolumbar compression fracture from January 2000 to June 2000. It was evaluated with simple Xray, bone scan, bone mineral density and CT for the patients 1)who had the compressed wedge fracture of vertebral body on simple X-ray, 2)who had increased bony uptakes of fracture site on bone scan, 3)who were under -2.5 in T-score on bone mineral density, 4)who were not relieved the pain to analgesic drug medication for more than 3 month with no radiating pain, 5)who had no fracture of posterior wall of vertebral body on CT in the case of acute fracture. We performed percutaneous vertebroplasty with bone cement and observed the degree of pain relief using pain scale pre-/ postoperation.
RESULTS
The average pain point decreased from 6.17 points to 1.06 points at postoperative 1 day, total decreased points were 5.11 points. The average pain point was 1.05 at postoperative 6 months in the patients followed up for more than 6 months.
CONCLUSION
Percutaneous vertebroplasty with bone cement is valuable method in the treatment of osteoporotic thoracolumbar compression fracture, providing pain relief, prevention of complication originated from long term traction and bed rest, unwearing brace and early ambulation

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Treatment of Combined Degenerative Lumbar Disease and Adjacent Vertebral Fracture
Jae-Lim Cho, IL-Hoon Sung, Seung-Wook Baek, Ye-Soo Park
Journal of Korean Society of Spine Surgery.2008; 15(4): 236. CrossRef

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Risk Factors in Progression of Deformity in Compression Fracture of Thoracolumbar Junction: Young Do Koh, Jong Oh Kim; J Korean Soc Fract 1999;12(2):372-378. Published online April 30, 1999; DOI: https://doi.org/10.12671/jksf.1999.12.2.372

Abstract PDF

Compression fracture of thoracolumbar junction is considered to be stable, and usually treated by conservative methods, such as bed rest followed by bracing. However, we can often see the progression of deformity during follow-up. Authors had treated 62 cases with compression fractures of thoracolumbar junction conservatively at Ewha Woman' University Mokdong Hospital from September, 1993 to December, 1997, and analyzed risk factors of progression in anterior vertebral height (AVH) collapse and kyphotic angle after the minimum 1 year follow-up. The results were as follows; The anterior vertebral height significantly more decreased in the group with age over 60, but increase of kyphotic angle was not related with age factor. In female, decrease of AVH and increase of kyphotic angle were more than in male. AVH significantly more decreased in L1 than in T12 or L2, but increase of kyphotic angle was not related with fracture level. Decrease of AVH and increase of kyphotic angle were not related with fracture type. Osteoporosis seems to be the most important single risk factor in progression of compression and more strict wearing of well-fitting brace is necessary to protect the progression in case of severe osteoporosis.

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The Influence of Initial Magnetic Resonance Imaging Findings on the Compression Rate of Thoracolumbar Osteoporotic Vertebral Compression Fracture
Seok-Ha Hwang, Seung-Pyo Suh, Young-Kyun Woo, Ho-Seung Jeon, Ho-Won Jeong
Journal of the Korean Orthopaedic Association.2018; 53(4): 341. CrossRef
Nonfusion Method in Thoracolumbar and Lumbar Spinal Fractures
Yong-Min Kim, Dong-Soo Kim, Eui-Sung Choi, Hyun-Chul Shon, Kyoung-Jin Park, Byung-Ki Cho, Jae-Jung Jeong, Young-Chan Cha, Ji-Kang Park
Spine.2011; 36(2): 170. CrossRef
The Efficacy of Kyphoplasty on Osteoporotic Vertebral Compression Fracture - A 1-Year Follow-up Study -
Dong-Ki Ahn, Song Lee, Dea-Jung Choi, Hoon-Seok Park, Kwan-Soo Kim, Tae-Woo Kim
Journal of Korean Society of Spine Surgery.2009; 16(2): 79. CrossRef
Clinical Outcome of Conservative Treatment for Osteoporotic Compression Fractures in Thoracolumbar Junction
Whoan Jeang Kim, Jong Won Kang, Kun Young Park, Jae Guk Park, Se Hyun Jung, Won Sik Choy
Journal of Korean Society of Spine Surgery.2006; 13(4): 240. CrossRef
Results of Non-fusion Method in Thoracolumbar and Lumbar Spinal Fractures
Yong-Min Kim, Dong-Soo Kim, Eui-Seong Choi, Hyun-Chul Shon, Kyoung-Jin Park, Kyeong-Il Jeong, Young-Chan Cha, Hu-Shan Cui
Journal of Korean Society of Spine Surgery.2005; 12(2): 132. CrossRef

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Diffrences of Bone Mineral Density between Osteoporotic Group with or without Compression Fracture of the Spine: Eu Sub Jung, Young Ki Lee, Seung Ill Baek; J Korean Soc Fract 1998;11(3):629-633. Published online July 31, 1998; DOI: https://doi.org/10.12671/jksf.1998.11.3.629

Abstract PDF

Osteoporosis is the metabolic bone disease and the bone is easily fracture by minimal stress due to decreased bone mass. It gets to attract more and more interest due to surprisingly high incidence and prevalence as well as its complications, fracture. We compared the bone mineral density between 45 osteoporotic patients group with compression fractures of the spine, 105 osteoporotic patients group without fractures and 45 normal control group using dual energy X-ray absorptiometry. We obtained following results. 1. There are statistically no significant differences between bone mineral density of the osteoporotic group with compression fracture of the spine and bone mineral density of the osteoporotic group without fractures. 2. Height and weight had statistically significant correlation with bone mineral density of the lumbar spine anteroposterior view, lateral view and Ward triangle. 3. Fracture threshold of the lumbar spine anteroposterior view, lateral wiew and Ward triangle are 0.884g/cm2, 0.694g/cm2 and 0.514g/cm2 according to 90percentile, 0.979g/cm2, 0.732g/cm2, 0.545g/cm2 according to 95percentile.

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Subsequent Hip Fracture in Osteoporotic Hip Fracture Patients
Sang Ho Lee, Tong Joo Lee, Kyu Jung Cho, Sang Hyun Shin, Kyoung Ho Moon
Yonsei Medical Journal.2012; 53(5): 1005. CrossRef

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